Glycogen Metabolism Published on August 31, 2020 by ehudspeth Glycogen Metabolism Skipping her normal balanced breakfast, Tammy was beginning to feel the burn one hour in to her midmorning marathon in downtown Chicago. Which of the following occurs during Glycogenolysis to maintain Tammy’s blood glucose levels and fuel exercising skeletal muscle during this event? Phosphorylation of Glycogen Phosphorylase by PKA Phosphorylation of Glycogen Synthase by Glycogen Phosphorylase Phosphorylation of Glycogen Phosphorylase by Phosphorylase Kinase Phosphorylation of Phosphorylase Kinase by Glycogen Phosphorylase Phosphorylation of Glycogen Synthase by Phosphorylase Kinase How much time does it take for glycogen to be depleted when one is in a basal state? 4-5 hours 12-14 hours 24-36 hours 1-2 days Glycogen is never depleted since the breakdown of all fuel sources contributes to glycogen stores A point mutation in glycogenin causes a stop codon to form where a tyrosine residue should be. Which of the following would you expect to see in a patient with this mutation? Inability to convert glucose-6P to glucose 1P Inability to convert glucose-1P to glucose-6P Inability to form glucose chains of glycogen Inability to form the branch points of glycogen Inability to break the glucose free from the glycogen chains. Time is Up!