Epithelium, Glands, & Skin Histology

Epithelium, Glands, & Skin Histology

The below image shows a pathological slide taken from the epididymis. Which of the following best describes the structure that the arrow is pointing to?


Primary cilitary dyskinesia, also called immotile ciliary syndrome, is a rare, autosomal recessive genetic disorderthat causes defects in the action of cilia. Which of the following is a NOT a consequence of this disease?


A patient presents to the clinic with a painful fever blister on his right toe. The doctor explains that if this continued, it would produce a protective thickening or hardening of the outer epithelium layers known as a callus. The doctor explains to the shadowing resident that this blister arose from one of the epidermal layers, which is a deep, single layer of cells that separates the dermis from the epidermis. Which of the following best describes this layer of cells?

The integumentary system is very essential in preventing water loss from the body, which would cause severe dehydration. One of the epidermal layers of the skin, the stratum granulosum, consists of 2 types of specific granules, each with a very important role. Which of the following is a lipid-rich structure located in the stratum granulosum that makes the epidermis impermeable to water, thus preventing dehydration?

What is the most appropriate diagnosis for someone with a congenital tyrosinase defect resulting in hypopigmentation of the skin?

The 5 layers of the epidermis consist of stratified squamous keratinized epithelium consisting of keratinocytes as well as many other cells. Some of the cells give rise to skin color, others are necessary for light touch, and some serve in immune function. These cells that assist in immunity are known as antigen presenting cells, and are made in the bone marrow, and then travel to the epidermis. They leave the epidermis and bind, process, and present antigens to T lymphocytes in the lymph nodes. Which of the following is most likely the cell type being described?

Identify the structure indicated by the crudely drawn arrow.

A patient comes to your office with a bladder infection. While performing your routine examination you notice that the patient is unable to sense coarse touch, pressure, and vibrations. You believe that this may be indicative of a defect in their:

After a long white coat weekend filled with family fun and studying, ARCOM students arrive at school Monday morning to find that their beloved coffee maker has been stolen! The security staff suspect an inside job as all of the cameras in the atrium were conveniently sabotaged. Which of the following anatomical features would be most helpful in allowing the security staff to narrow down a list of suspects:

An unlabeled tissue sample slide was found as seen above. Where in the body could this have come from?

Ta mako is a traditional Maori tattooing practice in which deep cuts are incised and then a chisel is dipped into pigment and tapped into cuts. This process leaves the tattoos with textured grooves instead of smooth skin seen in traditional tattooing. In which layer does this pigment reside?

As we age, type I collagen in which layer of skin begins to break down causing skin to lose its elasticity and become wrinkled?

Mutations in the gene OCA2 cause an autosomal recessive disorder that affects tyrosinase. Which of the following would you expect a patient with this mutation to present with?

Morphea is a form of localized scleroderma where waxy patches of varying sizes appear on the skin with thickened skin below. The skin in these areas are not able to feel a bug land on them. Which of the following mechanoreceptors is affected in morphea?

Which of the following is a difference between eccrine and apocrine sweat glands?

Epidermolysis bullosa is a disease that causes hemidesmosomes to break down causing formation of blisters and sloughing of skin. Which of the following stains would allow pathologists to see the hemidesmosomes?

Heavily glycosylated proteins would be expected to be released from which of the following?

Patients with Cystic Fibrosis (CF) often produce an increase in respiratory mucous due to a genetic disorder and increased chloride ion pumping into the extracellular fluid. An increase in this respiratory mucous makes it difficult for which of the following structures to function properly?

While performing a physical exam on your patient you notice what appears to be a bruise under the patient’s nail. The patient doesn’t remember any trauma that occurred to the phalange. You decide to trephinate it. It bleeds, but does not clear. This is most likely which of the following?

Rachel comes in to your office saying that almost everything she is eating is either giving her diarrhea or making her constipated. She has lost almost 15 pounds this month without trying. A blood test confirms that she has celiac disease. Why would changing her diet help to alleviate her symptoms?

Medications work by being able to get into the bloodstream, however many of these drugs would be lethal if they were to cross the blood-brain barrier. Which of the following junctions makes it so that these drugs cannot affect the integrity of the brain?

Pemphigus foliaceus is a dyshessive skin disorder caused by an autoimmune disease in which IgG autoantibodies from patients recognize desmogleins (Dsg), which are cadherin-type cell–cell adhesion molecules found in which of the following junctions?

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