Published on August 30, 2020 by ehudspeth Bone & Cartilage Histology The following photomicrographs shows the three various types of cartilage. Which of the following correctly labels the locations (in order) of the tissue from which these histological samples could have come from? Epiglottis, Trachea, annulus fibrosus Primary bronchus, epiglottis, nucleus pulposus Pinna of ear, pubic symphysis, annulus fibrosus Pinna of ear, pubic symphysis, nucleus pulposus Trachea, Epiglottis, annulus fibrosus Which of the following is NOT true regarding the cartilage matrix? Aggrecan serves to resist compression in the cartilage matrix The main glycosaminoglycans in the cartilage matrix include chondroitin, keratin sulfate, and hyaluronic acid Glycosaminoglycans are extremely hydrophobic Aggrecan is the most common proteoglycan found in cartilage The main glycoprotein in the cartilage matrix is chondronectin You hear some of your friends talking about the best wrestlers of all time. One of them states that Andre the Giant was a “natural Hulk.” You smirk and politely state that the reason he looked the way he did was not because he was a real live hulk, but rather: Rheumatoid Arthritis in the jaw Osteoblastoma pressing on his spinal cord Heterotrophic Ossification of his entire skeleton Acromegaly, a tumor on his anterior pituitary gland No, he was a real live hulk A patient comes into your clinic who had been previously diagnosed with osteoarthritis. In order to grade the severity of their condition, you decide to take a cartilage biopsy from the patients interphalangeal joints. Upon histological examination, you notice a discontinuity of the surface and loss of small portion of the superficial matrix. The slide that you are viewing is shown below. What stage of osteoarthritis is this patient in? Stage 1 Stage 2 Stage 3 Stage 4 Stage 5 A patient presents to your office with a painful swelling of the femur. After taking his history you find he has Paget Disease. You remember to Ms. Heather’s lectures regarding such symptoms and associated disease. What should you do next? Obtain an MRI to confirm/deny the possibility of Osteoblastoma Obtain a bone sample to confirm/deny the possibility of Osteoblastoma Obtain a CT to confirm/deny the possibility of Osteosarcoma Obtain an MRI to confirm/deny the possibility of Osteosarcoma Obtain a blood sample to confirm/deny the possibility of Osteosarcoma Which of the following is NOT true regarding the various cells within bone? Parathyroid hormone stimulates bone reabsorption via direct activation of osteoclasts Calcitonin inhibits osteoclast activity, decreasing blood calcium levels Osteoclasts can contain up to 50 nuclei Osteoblasts become osteocytes when they become entrapped in lacunae The development of osteoclasts and osteoblasts are inseparably linked Which of the following correctly identifies the cell specified in the following pictomicrograph? Osteocyte Osteoblast Chondrocyte Chondroblast Osteoclast Time is Up!