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BECOM 1 Exam 2 2019 – Hemostasis

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Jenna fell off her bike scraping her knee. This started a cascade of cellular processes: her knee started bleeding, turned red and was painful. Her broken endothelial cells release cytokines which signal thrombocytes to release more cytokines thus activating additional thrombocytes to clot and stop the bleeding. This is an example of:Deselect Answer

Returning to homeostasis

Anti-inflammatory response

Feed-forward activation

Anticoagulant response

Feedback inhibition

Which of the following is an example of a positive feedback mechanism?

Deselect Answer

Pyruvate dehydrogenase is inhibited by acetyl-CoA

Liver pyruvate kinase activity is up-regulated by fructose-1,6-bisphosphate

Stretch receptors in the cervix signal the pituitary to release oxytocin

Lactate is transported out of muscle tissue so that muscle lactate dehydrogenase can continue to recycle NAD+ against a low product concentration gradient

Which of the following would be a long-term effect of hemolytic anemia?Deselect Answer

Increase in bicarbonate

Haldane Effect

Increase in 2,3-BPG

Increase in erythropoietin

Bohr effect

Gene was recently diagnosed with hypertension and put on enalapril, an ACE inhibitor. He wants to know how it works, so you tell him, in layman’s terms:Deselect Answer

It blocks the formation of Renin which then prevents the body from creating a hormone called aldosterone which thus decreases blood pressure

It blocks a hormone that is secreted from the pituitary gland causing him to not absorb water thus decreasing blood pressure

It blocks an enzyme that prevents a hormone that tells the body to not absorb water thus decreasing blood pressure

It blocks an enzyme that prevents a hormone that tells the body to absorb water thus decreasing blood pressure

It blocks a hormone that is secreted from the pituitary gland causing him to absorb water thus decreasing blood pressure

In the cold northern winters, you many times will see people out at bars not wearing jackets who claim that they are not cold, is this problematic? Why or Why not?Deselect Answer

No, because hoes don’t get cold

Yes because their parasympathetic nervous system becomes activated which shunts blood to their core causing them to feel warmer while causing frostbite

No because Northerners have excess brown fat reserves

Yes, because the only reason they don’t feel cold is because they are shivering which causes muscle contractions which will not regulate body temperature

Yes because they feel warm because their body is vasodialating causing heat to leave their skin

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