Basic Mycology

Amphotericin B, an antifungal drug, targets the sterol in fungi cell membranes binding to it, thus creating a polar pore in fungal membranes. Which of the following does Amphotericin B most likely target?

  1. Cholesterol
  2. Ergosterol
  3. Chitin
  4. Peptidoglycan
  5. Sitosterol

Which of the following is the only fungi that has a capsule?

  1. Candida albicans
  2. Cryptococcus neoformans
  3. Aspergillus fumigatus
  4. Pneumocystis jiroveci
  5. Klebsiella

You are analyzing a specimen that was gathered from pulmonary abscess on a patient. The microorganism can be seen upon completion of an acid-fast stain. TB is suspected, but you come to find that the patient is negative following additional testing. Which of the following is most likely the culprit for the patient’s pulmonary symptoms?

  1. Aspergillus fumigatus
  2. Mycobacterium leprae
  3. Nocardia asteroides
  4. Mycobacterium leprae
  5. Histoplasma capsulatum